Surgical Notes
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Cleaning and Re-sterilization of DSI Implants Using Cold Sterilant
All new and exchanged transmitters shipped to an investigator are sterile and ready for implantation. In studies where transmitters are implanted for short periods, significant battery life may rem...
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Anesthesia Reference Manual
The attached manual is intended to be a guideline for selecting the proper anesthesia, analgesic and antibiotic regimens used in common laboratory animals. It does not account for every possible an...
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Biopotential Leads: What to Do with Them when Not Being Used
Users of multiple channel devices may occasionally choose not to use the biopotential leads. There is a recommended procedure for how to handle the unused leads to prevent surgical or electrical co...
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Can I re-sterilize my re-gel syringe(s)?
DSI doesn’t recommend re-sterilizing re-gel syringes, because the sterilization process (EtO) will change the properties of the gel, which may negatively affect data collection. DSI cannot guarante...
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Causes of Rat Hind Limb Paralysis
The following are potential causes of rat hind limb paralysis: Prolonged occlusion of the abdominal aorta – this is generally not a factor if flow is eventually fully restored Too much glue used t...
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Creating an Anesthesia Nosecone for Rodents
Select a “luer-lock“ syringe of the proper diameter for the animal species. The opening should fit around the snout between the nares and the eyes. Remove plunger and cut off the finger portion o...
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Device Explantation
It may be necessary to remove an implant intact, such as when it may be reused in another animal (following cleaning and re-sterilization), or if there have been any signal quality concerns and the...
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DSI Implantable Telemetry Products Sterility Testing
This report is intended to be given to customers who have an interest in understanding the effectiveness of the sterility process used by Data Sciences International on its Telemetry Product Implan...
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ECG Lead Placement in Large Quadrupeds
By: Dr. Craig Hassler, Battelle-Columbus, Columbus OH Good quality ECG recordings require proper lead placement technique. A technique developed and used at our lab meets the requirements for ease...
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Guidelines for the Regel of Mouse-Sized Catheters
The design of the mouse pressure transmitter (PA-C10, HD-X11 and HD-X10) provides optimum performance when monitoring physiologic pressures in small laboratory animals. The extreme sensitivity of t...
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Guidelines for the Regel of Small Animal Catheters
The design of the small animal pressure transmitter (HD-S10, HD-S11 and HD-S21) provides optimum performance when monitoring physiologic pressures in laboratory animals. The sensitivity of the devi...
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Guidelines for the Regel of the PhysioTel and PhysioTel Digital Large Animal Devices
The design of the pressure implant provides optimum performance when monitoring physiologic pressures in laboratory animals. The sensitivity of the device is largely dependent upon the terminal end...
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Implantation of a Mouse Pressure Device (PA-C10, HD-X10, or HD-X11) in Rats
Certain study requirements may involve smaller or juvenile rats, which will facilitate the need to use a mouse sized device. The device can be used to collect systemic blood pressure via the abdomi...
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Importance of Complete Circle of Willis in Mouse Surgeries
When performing the HD-X or HD-XG surgery in mice, it is important that the animal strain has a complete Circle of Willis. This surgery involves ligating the left common carotid artery and a comple...
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Large Animal Surgical Supplies
The attached document contains surgical supplies relevant for use with large animal DSI telemetry. A listing of supplies by device type is provided, as well as vendor and part number information. M...
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On-Site Cleaning and Decontamination of iPRECIO Pump and Programmer
All new iPRECIO infusion pumps shipped to an investigator are sterile and ready for implantation. DSI has developed procedures for cleaning and sterilizing iPRECIO pumps when returning them to DSI ...
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Post-Surgical Complications: Loss of Incision Integrity and Exposure of the Transmitter Body
Occasionally, following implantation of the DSI transmitter, an animal may experience poor wound healing and even extrusion of the transmitter. This situation can be avoided by using proper surgica...
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Preventing Damaged Sensors in Blood Pressure Implants
The pressure sensors in DSI’s blood pressure transmitters are delicate instruments and can be easily damaged. Therefore, it is necessary to use proper care when handling the transmitters. Below are...
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Proper Techniques for Maximizing the Use of the Suture Rib
The PhysioTel HD product line utilizes an external suture rib made of a flexible material that has been demonstrated to be effective in securing the transmitter body to the body wall. The suture ri...
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Recommendations to Prevent Hindlimb Paralysis in Large Animals
Hindlimb Paralysis may occur in the cannulated leg when the animal’s mean blood pressure value is lower than 60 mmHg for an extended period of time during the surgical procedure. Signs of hindlimb ...
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Recommended Instruments For Large Animal Surgery
The surgical instruments, along with their part numbers from Fine Science Tools, are listed below. Part Number Description 11006-12 Adson Forceps-straight, serrated 11027-12 Adso...
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Recommended Procedure for PA-C10, HD-X10, and HD-X11 to Determine the Correct Insertion Depth for Mouse Carotid
To maintain catheter patency throughout the length of a study, the catheter tip should be located in the freely-flowing blood of the aortic arch. Depending on the mouse strain, gender, age and size...
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Seromas: Cause and Management
Following subcutaneous implantation of medical devices, seromas can develop due to several causes. When seromas do occur, proper medical management may prevent further complications. Anyone who ha...
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Small Animal Minimum Weight at Implant Requirements
Mouse Minimum Weight Transmitter IP (grams) SQ (grams) HD-X02 25 19 HD-XG 25 carotid 19 HD-X10 25 19 HD-X11 25 19 PA-C10 30 abdominal aorta NA PA-C10 25 carotid 17 TA-F10 20 17 E...
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Small Animal Surgical Supplies
The PDF document below contains recommended surgical supplies relevant for use with small animal DSI telemetry. A listing of supplies by device type is provided as well as vendor and part number in...
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Small Animal Trocar and Sleeve Dimensions
TrocarLength 165.1 mm or 16.51 cmDiameter 2.65 mm Trocar SleeveLength 142 mm or 14.2 cmDiameter 3 mm
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Surgical Recommendations to Optimize Femoral/Iliac Artery Cannulation
Due to its size, location, and ease of access, the femoral artery is frequently used for blood pressure catheter placement. Less frequently, the catheter is inserted directly into an iliac artery. ...
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Tips on Maintaining Animal Comfort
Data Sciences International (DSI) transmitters have been proven, through years of testing and use, to be very biocompatible. Under normal use and when following correct surgical techniques, these ...
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Vetbond Storage and Self-life
Vetbond(TM) Tissue Adhesive has a 18-24 month shelf life depending on how it is stored. It is recommended to store in a cool, dry place and to maintain product at room temperature. Once opened, it ...
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